Scandinavian Study Shows Radical Prostatectomy Results in Lowered Cancer Death Rate
Abstracted from Associated Press via CNN Interactive
A RANDOMIZED TRIAL COMPARING RADICAL PROSTATECTOMY
WITH WATCHFUL WAITING IN EARLY PROSTATE CANCER
Lars Holmberg et al, New Engl J Med 347, 781, 2002.
CNN/9-12-02---Swedish scientists have demonstrated---for the first time--- that radical prostatectomy reduces the death rate from prostate cancer (CaP). The landmark study, completed between 1989 and 1999, was published in the September 12, 2002 issue of the New England Journal of Medicine. 695 Scandinavian men with localized CaP were randomly assigned to treatment by radical prostatectomy or observation alone. After a median follow-up of 6.2 years, 8.9% of the observed men had died from CaP vs 4.6% of those treated by radical prostatectomy. Relative reduction of risk (CaP death or metastastatic disease) was approximately 50%.
In an accompanying editorial, Patrick C. Walsh of Johns Hopkins University---father of the modern radical prostatectomy---made the following comments: