This page is being served from the Urological Sciences Research Foundation web repository, and was originally posted between 1996-2008. In January 2009 USRF’s founder, Dr. Leonard S. Marks and his staff joined UCLA’s Department of Urology where they are continuing their research. Click for more information.
New Guidelines for PSA Testing
by American Urological Association (AUA)
Leonard S. Marks, M.D.
1st Quarter, 2000 - Baltimore, MD (February 22, 2000)---A "Best Practice Policy" for use of PSA testing was issued by the American Urological Association (AUA) today. The policy, which was developed by a multidisciplinary panel of 8 and peer reviewed by 47 experts from urology, internal medicine, gerontology, oncology, and radiation therapy, appears to establish major guidelines for the foreseeable future. The entire policy was published in the February issue of Oncology and is publicly available online free at http://www.cancernetwork.com. Measuring blood levels of PSA (prostate specific antigen) is now the commonest means of detecting prostate cancer. The diagnosis must be subsequently established by biopsy, since the PSA test is not specific for cancer. According to Ian Thompson, M.D., the chairman of the panel of experts, the new policy report distills available data about PSA "…down to a short, easy to digest balanced document on what we know about the subject relating to the diagnosis, staging, and management of prostate cancer." Of all prostate cancers currently detected, approximately 75% are associated with an abnormal PSA test.
Regarding early detection of prostate cancer, the expert panel concluded
that routine PSA testing shoudl be offered in men when:
Regarding prostate biopsy, the panel concluded that this is indicated when:
Regarding use of PSA testing in the staging of men with known prostate cancer, the experts concluded:
Regarding use of PSA testing in the follow-up of men after treatment for prostate cancer, the panel members determined the following:
The PSA test was first brought to market in 1986 by Hybritech, Inc., which is now a division of Beckman Coulter, Inc. Additional sources of PSA information are available online at the following websites:
Selected USRF publications relating to PSA:
American Cancer Society
AUA Patient Education brochure: