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Slide 15 of 18

5ARI drugs reduce the risk of acute urinary retention (AUR). The MTOPS study (Medical Therapy of Prostatic Symptoms) showed that compared to alpha-blockers, a 5ARI drug finasteride reduced the risk of AUR. Symptomatic relief was greatest with both drugs used together, but protection from BPH disease was primarily related to the 5ARI component.

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