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Slide 11 of 14

 
Foible No. 8. Inflammation of the prostate can cause marked increases in serum PSA levels. The chart above shows the time course of total and %Free PSA levels in serum of a 47 y.o. physician who presented with typical signs and symptoms of acute prostatitis. His initial PSA was 27 ng/ml and % Free was only 6%. Both levels are highly suggestive of prostate cancer, but with antibiotic therapy, and the passage of many weeks, the levels returned to normal. Thus, inflammation may be another cause of a false reading, if PSA were considered a prostate cancer test, ie, Foible 8.

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